3 Nov 2016 Effect of sphingosine 1-phosphate receptor 1 (S1PR1) agonism on murine pertussis disease. A, B, Relative gene expression levels of

General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. S1PR1. Gene descriptioni.

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all spec The following S1pr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the S1pr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence.

S1pr1 gene

Alliance ; Gene:64617 ; VEGA:OTTDARG00000012039 Summaries for S1PR1 gene (According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL) About This Sectio DGIdb, The Drug Gene Interaction Database, is a research resource that can be used to search candidate genes or drugs against the known and potentially druggable genome. Search Search Interactions Search Categories S1PR1 (sphingosine-1-phosphate receptor 1), also known as S1P1, EDG1 and CD363, is a 7-transmembrane protein of the G protein-coupled receptor 1 (GPCR1) family. S1PR1 is highly expressed in endothelial cells and binds the ligand sphingosine-1-phosphate (S1P) with high affinity and high specificity. Plasmid S1PR1-Tango from Dr. Bryan Roth's lab contains the insert S1PR1 and is published in Nat Struct Mol Biol.

(from RefSeq NM_001400) RefSeq Summary (NM_001400): The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be NCBI Gene:1901 S1PR1.

I synnerhet kan nedreglering av S1PR1 representera den huvudsakliga assay kit (Affymetrix)) and hybridized to a mouse gene 1.0 ST array (Affymetrix).

doi: 10.1038/nsmb.3014. Epub 2015 Apr 20.

S1P1 is a G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that is coupled to the G (i) subclass

The S1PR1 gene encodes a receptor for the lysosphingolipid sphingosine-1-phosphate (S1P). There are 5 known S1P receptors with distinct but overlapping regulatory functions in normal physiology and disease processes, particularly involving the immune, central nervous, and cardiovascular systems. Also known as: S1pr1 tm3.1(tTA,-Arrb2)Rlp, S1P1 Tango mouse These S1pr1 knockin mice have a bicistronic transcription unit inserted at the C-terminus of exon 2 of the sphingosine-1-phosphate receptor 1 (S1pr1) gene. STAT3 is a transcription factor for the S1pr1 gene. Reciprocally, enhanced S1pr1 expression activates STAT3 and upregulates Il6 gene expression, thereby accelerating tumor growth and metastasis in a STAT3-dependent manner. Silencing S1pr1 in tumor cells or immune cells inhibits tumor STAT3 activity, tumor growth and metastasis.

View mouse S1pr1 Chr3:115710433-115715055 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression. Home.
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COSMIC gene S1PR1 (COSG55025) Genomic coordinates 1:101236888..101241518 (positive strand) Synonyms CD363, D1S3362, EDG1, edg-1, CCDS777.1, P21453, ENSG00000170989.8, NM_001400.4, NP_001391,NP_001307659 COSMIC-3D Plasmid S1PR1-Tango from Dr. Bryan Roth's lab contains the insert S1PR1 and is published in Nat Struct Mol Biol. 2015 May;22(5):362-9.

Activation of this S1PR1: HGNC i: HGNC:3165, S1PR1: HPA i: ENSG00000170989, Tissue enhanced (blood) MIM i: 601974, gene: neXtProt i: NX_P21453: OpenTargets i: ENSG00000170989: PharmGKB i: PA162402344: VEuPathDB i: HostDB:ENSG00000170989.8: GenAtlas i: Search General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. S1PR1.
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Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1P1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded

Find diseases associated with this biological target and compounds tested against it in bioassay experiments. s1pr1 sphingosine-1-phosphate receptor 1 The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells.